Main information about Diflucan
Diflucan is an effective antifungal drug which contains Fluconazole.
An antifungal action is conditioned by the influence of Diflucan to the protein molecules (RNA) of fungi. The active ingredients penetrate into the cells of fungi, enhance a permeability of the cellular membrane (due to which a content of the cells become vulnerable by the external factor) and cause lysis of the fungi molecules.
An advantage of Diflucan consists in achieving a fast medical effect. In the treatment of some fungal infections, a therapeutic effect is achieved after a one-time use of the drug. But if a disease is chronic because of the incorrect or delayed treatment, Diflucan should be used within a long time occasionally.
Another important advantage of Diflucan consists in its high safety. This drug may be used during oncological diseases and AIDS.
Diflucan shows a higher activity as to fungi from the group of Candida and is often used in the treatment of candidiasis. But besides this disease, Diflucan may be used in the treatment of:
- cryptococcal meningitis
- fungal diseases of the lungs, skin
- all forms of candidiasis
Diflucan is indicated to prevent fungal infections during the antibacterial therapy.
Use and dose of Diflucan
The daily dose of Diflucan depends on the type of the fungal infection and severity of the disease. The treatment should be continued till the complete disappearance of the fungal infection symptoms, and therefore it is necessary to take the tests after the end of the planned cycle of the treatment and make sure in the inhibition of the fungi activity.
To treat vaginal candidiasis, it is necessary to take a pill of Diflucan 150 mg once. To prevent relapses, it is recommended to take a pill of Diflucan 150 mg every month within a year.
To treat candidiasis of the skin, mycosis and fungal diseases of the lungs, Diflucan 150 mg is taken once per week within 1-2 weeks.
To treat cryptococcal meningitis, patients are prescribed Diflucan 400 mg in this first day, and then the treatment is continued in the dose of 200 mg of Diflucan per day within 6-8 weeks.
To prevent candidiasis during the antibacterial therapy, it is necessary to take a pill of Diflucan 150 mg every 3 days up to the end of the use of the antibiotics.
Recommendations for the use
- An early termination of the treatment before the confirmation of the remission of the fungal infection may cause a relapse
- The treatment may be started before having the laboratory tests
- Diflucan may cause an additional load to the liver and hepatotoxic reaction in patients with hepatic failure. The load to the liver is reduced after the end of the drug administration
- Diflucan is allowed during pregnancy but the treatment should be controlled by a doctor. If the side effects appear, the treatment is stopped
Diflucan has a high safety status and does not cause side effects in most cases. In rare cases, using high doses of Diflucan patients may experience the following side effects: diarrhea, nausea, dizziness, and muscle cramps.