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Main information about Celebrex

Celebrex stops an inflammatory process and reduces pain during the degenerative diseases of the musculoskeletal system. It has an ingredient Celecoxib.

Celebrex is a non-steroid anti-inflammatory drug which has pain-relieving, antifebrile action. It blocks a formation of the inflammatory prostaglandins and reduces biochemical processes causing pain in the sites of the inflammation.

The maximal therapeutic effect of Celebrex occurs in 2 hours after the use of a one-time therapeutic dose. The action of this dose lasts for 10 to 12 hours depending on the speed of the metabolism of a patient.

The use of Celebrex causes a reduction of the symptoms of the inflammatory diseases of the musculoskeletal system: pain is reduced, the movement of the joints is improved, feeling of fever in joints disappears. Unlike most nonsteroid anti-inflammatory drugs, Celebrex poorly affects the functions of the gastro-intestinal tract and a degree of the production of the gastric juice. Therefore this drug is allowed for patients with ulcers of the stomach and duodenum.

Celebrex may be used during the different inflammatory diseases of non-infectious origin, but  this drug provides the highest activity during:

  • Osteoarthritis
  • Rheumatoid arthritis
  • ankylosing spondylitis
  • pain during the postoperative period
  • primary dysmenorrheal

Administration and dose of Celebrex

Celebrex should be used for a short period in order to reduce cardiovascular complications and ease the work of the liver that excretes the active ingredients of Celebrex from the body.

To treat the inflammatory diseases of the musculoskeletal system, it is recommended to take a pill of Celebrex 200 mg 1-2 times per day (depending on the severity of the symptoms and painful syndrome).

The maximal daily dose of Celebrex is 400 mg. The recommended length of the use of Celebrex is 2-3 weeks. To prolong the treatment, it is necessary to replace NSAID or take a break in the treatment for at least 10 days.

Senior patients (who do not have severe chronic diseases of kidneys/liver/heart) should not lower the daily dose.

Recommendations for the use

  • if you feel severe pain in the stomach or gastric bleedings during the use of Celebrex, it is necessary to go to a doctor. Take the medicine carefully during the inflammatory diseases of the intestine
  • if you have had a severe allergic reaction to NSAID, acetylsalicylic acid, the use of Celebrex is contraindicated
  • Celebrex is contraindicated during severe diseases of the cardiovascular system: ischemic heart disease, heart failure and others
  • Do not take Celebrex if you are pregnant

Side effect

The side effects of Celebrex are reversible and pass after the end of the therapy. But the use of Celebrex is often accompanied by the following side effects: tingling, lack of energy, skin allergic reactions, diarrhea, stomachache, infections of the respiratory tracts, and loss of taste.

If the side effects bother you, lower the dose of Celebrex for a while.