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What is Paxil?

Paxil is a trade name of the active ingredient Paroxetine which has an expressed antidepressant action with minimal quantity of the side effects.

The antidepressive activity of Paxil is conditioned by the specific selective serotonin reuptake inhibition in the neurons of the brain. The increase of serotonin in the neurons of the brain regulates pathogenic factors of the depression development.

Paxil is a typical serotonin reuptake inhibition but in spite of this, it differs from the common tricyclic and tetracyclic antidepressants. Paroxetine selectively acts to the receptors of serotonin without affecting dopamine and histamine receptors in the brain. As a result, taking Paxil causes less inhibition of the central nervous system and no hypotensive effect.

Paxil not only reduces the depression symptoms but also neutralizes anxiety, and helps to restore sleep in case of insomnia. It is possible due to the cholynolytic effect.

Unlike most advanced antidepressants, Paxilacts gradually and provides a mild action to the body. The patient will not feel the intense action of the medication the next day, but it gives an opportunity to avoid such side effects as nausea, vomiting, and dizziness.

Who is prescribed Paxil?

Paxil antidepressant is prescribed patients for:

  • Depressive disorder of any type and origin (acute depression, chronic depression, etc)
  • Depressions accompanied by anxiety
  • Obsessive-compulsive disorder
  • Preventive measures and treatment of the panic disorders

Paxil can be also used for the expressed insomnia, in the setting of stress, post-traumatic and depressive disorders.

How to take Paxil?

  • The standard daily dose of Paxil is 20 mg for the treatment of the depression.
  • The pills of Paxil 20 mg should be taken once per day, in the morning, during or after meals
  • In case of no antidepressive effects within 2 weeks of Paxil 20 mg application, the daily dose may be increased by 10 mg.
  • The maximal daily dose of Paxil can be 50 mg for the depression treatment
  • The daily dose of Paxil should be increased with interval of 1 week.
  • For obsessive-compulsory disorders and panic disorders, the initial daily dose should be at least 40 mg of Paxil.
  • For anxious disorders, insomnia, and other psychological disorders, the optimal dose is 1 pill of Paxil 20 mg.

Paxil does not provide an expressed soporific effects but it gives a light sedative one. Therefore, the medication is ineffective to arrest acute attacks of insomnia, and acts only for the accumulative effect.


The use of Paxil, as any other strong antidepressant, should be controlled by a qualified doctor. The adherence to the precautions will reduce the probability of the side effects and increase the efficiency of the antidepressant therapy.

  • Avoid sudden termination of the medicine administration. It will cause a relapse of the depression symptoms and severe anxiety
  • Do not take beverage drinks which provide an expressed suppressive action to the CNS during the treatment
  • Paxil is incompatible with MAO inhibitors
  • Taking Paxil with other serotonin reuptake inhibitors the doses of both medicines should be reduced
  • Taking Paxil during pregnancy increases the risk of the congenital defects in children, and therefore pregnant women have to refuse from the application of the medication
  • Some parts of paroxetine penetrate into the breast milk. Paxil must not be taken during the breast feeding.

Possible side effects

The absence of the expressed side effects makes Paxil one of the most attractive antidepressants. However, patients may still have negative reactions of the body to the action of this medication.

Low appetite, sleepiness, blurred vision, convulsion, diarrhea, dry mouth, sexual dysfunction, and asthenia are the side effects which may happen during the use of Paxil.